Sunday, November 6, 2011

Starting out from Citrate: a poem about the Krebs cycle.

STARTING OUT FROM CITRATE

First, a rearrangement.
Then, Boom! Boom! Two explosions, each exhaling; each reduces NAD+.
In the second, CoA enters.

CoA is displaced by water; GTP is made.

Fumarate is made by reducing FAD.

Fumarate is thirsty, has a drink, and turns to Malate.

A final oxidation, NAD+ again reduced: Oxaloacetate!

Which then combines with acetate (CoA once again displaced by water):
Starting out from Citrate once again.

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